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    2010”NˆÈ~‚̘_•ĥ

 

Transl Psychiatry. 2017 Feb 28;7(2):e1047. doi: 10.1038/tp.2017.19.

                Schizophrenia-like phenotypes in mice with NMDA receptor ablation in intralaminar thalamic nucleus cells and gene therapy-based reversal in adults

                Yasuda K, Hayashi Y, Yoshida T, Kashiwagi M, Nakagawa N, Michikawa T, Tanaka M, Ando R, Huang A, Hosoya T, McHugh TJ, Kuwahara M, Itohara S

 

Science  2016 30 Sep 353, 6307, 1536-1541 DOI: 10.1126/science.aaf7003

                Ventral CA1 neurons store social memory

                Okuyama T, Kitamura T, Roy DS,  Itohara S, Tonegawa S.

 

Neurobiol Learn Mem. 2016 Jul 1. pii: S1074-7427(16)30101-0

                Cognitive deficits in single App knock-in mouse models.

                Masuda A, Kobayashi Y, Nogo N, Saito T, Saido TC, Itohara S.

 

Sci Rep  2016 June 6:28750 doi: 10.1038/srep28750.

                Netrin-G1 regulates fear-like and anxiety-like behaviors in dissociable neural circuits.

                Zhang Q, Sano C, Masuda A, Ando R, Tanaka M, Itohara S.

 

Mol Brain 2016 Jan 8;9(1):6 doi: : 10.1186/s13041-016-0187-5.

                Diversification of behavior and postsynaptic properties by netrin-G presynaptic adhesion family proteins.

                Zhang Q, Goto H, Akiyoshi-Nishimura S, Prosselkov P, Sano C, Matsukawa H, Yaguchi K, Nakashiba T, Itohara S.

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Science 2015 Nov 22. aad1023. DOI: 10.1126/science.aad1023

                Cells of a common developmental origin regulate REM/non-REM sleep and wakefulness in mice .

                Hayashi Y, Kashiwagi M, Yasuda K, Ando R, Kanuka M, Sakai K, Itohara S.

                 Go to Press Release(Japanese)

 

Mol Brain. 2015 Jun 24;8:38. doi: 10.1186/s13041-015-0130-1.

                Involvement of cAMP-guanine nucleotide exchange factor II in hippocampal long-term depression and behavioral flexibility.

                Lee K, Kobayashi Y, Seo H, Kwak JH, Masuda A, Lim CS, Lee HR, Kang SJ, Park P, Sim SE, Kogo N, Kawasaki H, Kaang BK, Itohara S.

 

  The Journal of Neuroscience. 2014 Sep 3;34(36):12001-14. doi: 10.1523/JNEUROSCI.1663-14.2014.

                Thalamic NMDA Receptor Function Is Necessary for Patterning of the Thalamocortical Somatosensory Map

                and for Sendorimotor Behaviors.

                Arakawa H, Suzuki A, Zhao Shuxin, Tsytsarev V, Lo FS, Hayashi Y, Itohara S, Iwasato T, Erzurumlu RS.

 

  Cell Rep. 2014 Aug 21. pii: S2211-1247(14)00631-7. doi: 10.1016/j.celrep.2014.07.047.

                RacGAP ƒż2-Chimaerin Function in Development Adjusts Cognitive Ability in Adulthood.

                Iwata R, Ohi K, Kobayashi Y, Masuda A, Iwama M, Yasuda Y, Yamamori H, Tanaka M, Hashimoto R, Itohara S, Iwasato T.

                 Go to Press Release(Japanese)

 

    Neuron. 2014 Mar 25. pii: S0896-6273(14)00157-3. 

                NMDAR-Regulated Dynamics of Layer 4 Neuronal Dendrites during Thalamocortical Reorganization in Neonates.

                Mizuno H, Luo W, Tarusawa E, Saito YM, Sato T, Yoshimura Y, Itohara S, Iwasato T.

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      Mol Brain. 2014 Mar 19;7:19. doi: 10.1186/1756-6606-7-19.

                Identification of transcriptional regulatory elements for Ntng1 and Ntng2 genes in mice.

                Yaguchi K, Nishimura-Akiyoshi S, Kuroki S, Onodera T, Itohara S.

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    J Neurosci. 2014 Mar 12;34(11):3841-53. doi: 10.1523/JNEUROSCI.4992-13.2014.

                Spinal Glutamatergic Neurons Defined by EphA4 Signaling Are Essential Components of Normal Locomotor Circuits

                    Borgius L, Nishimaru H, Caldeira V, Kunugise Y, Löw P, Reig R, Itohara S, Iwasato T, Kiehn O.

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    Cell Calcium. 2014 Feb;55(2):119-29. doi: 10.1016/j.ceca.2013.12.006. Epub 2014 Jan 8.

                Spatiotemporal calcium dynamics in single astrocytes and its modulation by neuronal activity

                    Wu YW, Tang X, Arizono M, Bannai H, Shih PY, Dembitskaya Y, Kazantsev V, Tanaka M1, Itohara S, Mikoshiba K, Semyanov A.

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      J Cell Sci. 2013 Nov 1;126(Pt 21):4926-38. doi: 10.1242/jcs.129718. Epub 2013 Aug 28.

                Trans-induced cis interaction in the tripartite NGL-1, netrin-G1 and LAR adhesion complex promotes development of excitatory synapses.

                Song YS, Lee HJ, Prosselkov P, Itohara S, Kim E.

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      Front Behav Neurosci. 2013; 7: 17.

               Genetic dissection of medial habenula–interpeduncular nucleus pathway function in mice

               Kobayashi Y, Sano Y, Vannoni E, Goto H, Suzuki H, Oba A, Kawasaki H, Kanba S, Lipp HP, Murphy NP, Wolfer DP, Itohara S.

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     Mol Brain. 2013 Jan 28;6:6. doi: 10.1186/1756-6606-6-6.

               Astrocytic Ca2+ signals are required for the functional integrity of tripartite synapses

                Tanaka M, Shih PY, Gomi H, Yoshida T, Nakai J, Ando R, Furuichi T, Mikoshiba K, Semyanov A, Itohara S.

      PLoS One. 2012;7(4):e35676. Epub 2012 Apr 20.

                Restoration of contralateral representation in the mouse somatosensory cortex after crossing nerve transfer.

                Yamashita H, Chen S, Komagata S, Hishida R, Iwasato T, Itohara S, Yagi T, Endo N, Shibata M, Shibuki K.

    J Comp Neurol. 2011 Nov 18. doi: 10.1002/cne.23000. 520: 7: 1562–1583

                Role of adenylate cyclase 1 in retinofugal map development.

                Dhande OS, Bhatt S, Anishchenko A, Elstrott J, Iwasato T, Swindell EC, Xu HP, Jamrich M, Itohara S, Feller MB, Crair MC.

    J Neurosci. 2011 Sep 7;31(36):12963-71.

                Matrix metalloproteinase-9 contributes to kindled seizure development in pentylenetetrazole-treated mice by converting pro-BDNF to mature BDNF in the hippocampus.

                Mizoguchi H, Nakade J, Tachibana M, Ibi D, Someya E, Koike H, Kamei H, Nabeshima T, Itohara S, Takuma K, Sawada M, Sato J, Yamada K.

    J Neurosci. 2011 Apr 20;31(16):5893-904.

                NMDA receptors in hippocampal GABAergic synapses and their role in nitric oxide signaling.

                Szabadits E, Cserép C, Szonyi A, Fukazawa Y, Shigemoto R, Watanabe M, Itohara S, Freund TF, Nyiri G.

    Mol Brain. 2011 Apr 13;4:14.

                Identification of a novel intronic enhancer responsible for the transcriptional regulation of musashi1 in neural stem/progenitor cells.

                Kawase S, Imai T, Miyauchi-Hara C, Yaguchi K, Nishimoto Y, Fukami S, Matsuzaki Y, Miyawaki A, Itohara S, Okano H.

    Neurosci Lett. 2011 Feb 11;489(3):148-53. Epub 2010 Dec 10.

                Normal delay eyeblink conditioning in mice devoid of astrocytic S100B.

                Kim HS, Seto-Ohshima A, Nishiyama H, Itohara S.

    J Biol Chem. 2010 Dec 31;285(53):41380-90. Epub 2010 Oct 21.

                Brain-specific Phgdh deletion reveals a pivotal role for L-serine biosynthesis in controlling

the level of D-serine, an N-methyl-D-aspartate receptor co-agonist, in adult brain.

                Yang JH, Wada A, Yoshida K, Miyoshi Y, Sayano T, Esaki K, Kinoshita MO, Tomonaga S, Azuma N,

                Watanabe M, Hamase K, Zaitsu K, Machida T, Messing A, Itohara S, Hirabayashi Y, Furuya S.

    Int J Mol Med. 2010 Dec;26(6):845-51.

                Enhanced enteric invasion of scrapie agents into the villous columnar epithelium via maternal immunoglobulin.

                Ano Y, Sakudo A, Uraki R, Sato Y, Kono J, Sugiura K, Yokoyama T, Itohara S, Nakayama H, Yukawa M, Onodera T.

    J Virol. 2010 Jul;84(13):6654-66. Epub 2010 Apr 21.

                Role of mouse hepatitis virus (MHV) receptor murine CEACAM1 in the resistance of mice to MHV@infection: studies of mice with chimeric mCEACAM1a and mCEACAM1b.

                Hirai A, Ohtsuka N, Ikeda T, Taniguchi R, Blau D, Nakagaki K, Miura HS, Ami Y, Yamada YK, Itohara S, Holmes KV, Taguchi F.

    J Biol Chem. 2010 Apr 16;285(16):11931-6. Epub 2010 Feb 22.

              Tracing conformational transition of abnormal prion proteins during interspecies transmission by using novel antibodies.

              Ushiki-Kaku Y, Endo R, Iwamaru Y, Shimizu Y, Imamura M, Masujin K, Yamamoto T, Hattori S, Itohara S, Irie S, Yokoyama T.

      J Neurochem. 2010 Feb;112(4):1035-44. Epub 2009 Dec 3.

              Molecular characterization and gene disruption of a novel zinc-finger protein, HIT-4, expressed in rodent brain.

              Tanabe Y, Hirano A, Iwasato T, Itohara S, Araki K, Yamaguchi T, Ichikawa T, Kumanishi T, Aizawa Y, Takahashi H, Kakita A, Nawa H.

      

            Front. Behav. Neurosci. 2010 Apr 19;4:17.

            Involvement of cyclin-dependent kinase-like 2 in cognitive function required for contextual and spatial learning in mice

            Gomi H, Sassa T, Thompson RF, and Itohara S.

      J Biol Chem. 2010 Feb 22. [Epub ahead of print]

              Tracing of conformational transition of abnormal prion proteins during interspecies transmission by using novel antibodies.

              Ushiki-Kaku Y, Endo R, Iwamaru Y, Shimizu Y, Imamura M, Masujin K, Yamamoto T, Hattori S, Itohara S, Irie S, Yokoyama T.
   

     J. Neurochem., 112(4), 1035-1044, 2010. 

@@@@@@Molecular characterization and gene expression of a novel zinc-finger protein, HIT-4, expressed in rodent brain. 

@@@@@@Tanabe Y, Hirano A, Iwasato T, Itohara S, Araki K, Yamaguchi T, Ichikawa T, Kumanishi T, Aizawa Y, Takahashi H, Kakita A and Nawa H.


     Brain Res., 1312, 156-167, 2010.

@@@@@@Role of GFAP in morphological retention and distribution of reactive astrocytes induced by scrapie encephalopathy in mice. 

@@@@@@Gomi H, Yokoyama T and Itohara S.


    
Neuroscience 165(1): 138-150, 2010.

@@@@@@Genetic disruption of the alternative splicing of drebrin gene impairs context-dependent fear learning in adulthood.

@@@@@@Kojima N, Hanamura K, Yamazaki H, Ikeda T, Itohara S and Shirao T.
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    ˜_•ĥ 2010-

    ˜_•ĥ 2005-2009

    ˜_•ĥ 1998-2004

    ˜_•ĥ 1978-1997

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